Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:

MAP kinase-activated protein kinase 2 (MAP kinase-activated protein kinase 2 (EC 2.7.1.-) (from PhosphoBase))

Seq-ID:

P49137 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-2833388 LIMK1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding, signal transducer activity, protein binding	cytosol, nucleus	protein amino acid phosphorylation, MAPKKK cascade, Ras protein signal transduction

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	9	MLSNSQGQSPPVPFPAPAP	MAPK1	8846784	LTP	0.09	MOD_ProDKin_1	-	-	0.84	-	-
T	25	PAPAPPPQPPTPALPHPPAQP	MAPK_group	8846784	LTP	0.03	MOD_ProDKin_1	-	-	0.95	-	-
T	25	PAPAPPPQPPTPALPHPPAQP	MAPK14	8846784	LTP	0.03	MOD_ProDKin_1	-	-	0.95	-	-
Y	63	QIKKNAIIDDYKVTSQVLGLG	-	17287340	HTP	1.00		-	-	0.25	2OZA	1.75%
T	222	KETTSHNSLTTPCYTPYYVAP	MAPK_group	8846784	LTP	0.95	MOD_ProDKin_1	-	S_TKc	0.26	2OZA	39.04%
T	222	KETTSHNSLTTPCYTPYYVAP	MAPK14	8846784	LTP	0.95	MOD_ProDKin_1	-	S_TKc	0.26	2OZA	39.04%
T	222	KETTSHNSLTTPCYTPYYVAP	-	18669648	HTP	0.95	MOD_ProDKin_1	-	S_TKc	0.26	2OZA	39.04%
S	272	PFYSNHGLAISPGMKTRIRMG	MAPK_group	8846784	LTP	1.00	MOD_ProDKin_1	-	S_TKc	0.29	1KWP	51.64%
S	272	PFYSNHGLAISPGMKTRIRMG	MAPK14	8846784	LTP	1.00	MOD_ProDKin_1	-	S_TKc	0.29	1KWP	51.64%
T	334	WIMQSTKVPQTPLHTSRVLKE	MAPK_group	8846784	LTP	0.93	MOD_ProDKin_1	-	-	0.49	2OZA	19.86%
T	334	WIMQSTKVPQTPLHTSRVLKE	MAPK14	8846784	LTP	0.93	MOD_ProDKin_1	-	-	0.49	2OZA	19.86%
T	334	WIMQSTKVPQTPLHTSRVLKE	-	16456544	LTP	0.93	MOD_ProDKin_1	-	-	0.49	2OZA	19.86%
T	338	STKVPQTPLHTSRVLKEDKER	MAPKAPK2	8846784	LTP	0.87		-	-	0.55	2OZA	0.00%

Substrate:

MAP kinase-activated protein kinase 2 (MAP kinase-activated protein kinase 2 (EC 2.7.1.-) (from PhosphoBase))

Seq-ID:

P49138 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-7265076 MK14_MOUSE
MINT-7265089 PHC2_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding	cytoplasm, nucleus	protein amino acid phosphorylation, mRNA stabilization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	208	KETTSHNSLTTPCYTPYYVAP	MAPK3	7592979	LTP	0.95	MOD_ProDKin_1	-	S_TKc	0.26	-	-
T	208	KETTSHNSLTTPCYTPYYVAP	-	17242355	HTP	0.95	MOD_ProDKin_1	-	S_TKc	0.26	-	-
T	320	WIMQSTKVPQTPLHTSRVLKE	MAPK3	7592979	LTP	0.93	MOD_ProDKin_1	-	-	0.49	2PZY	30.82%
T	320	WIMQSTKVPQTPLHTSRVLKE	-	17242355	HTP	0.93	MOD_ProDKin_1	-	-	0.49	2PZY	30.82%
T	324	STKVPQTPLHTSRVLKEDKER	-	17242355	HTP	0.87		-	-	0.56	2PZY	0.68%

Substrate:

MAP kinase-activated protein kinase 2 (MAP kinase-activated protein kinase 2 (EC 2.7.1.-) (from PhosphoBase))

Seq-ID:

P49139 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein serine/threonine kinase activity, ATP binding		protein amino acid phosphorylation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	300	WIMQSTKVPQTPLHTSRXXXX	MAPK_group	1327754	LTP	0.92	MOD_ProDKin_1	-	-	0.56	-	low